Tranexamic Acid (TXA)

Tranexamic Acid

The CRASH-2 2 (Clinical Randomisation of an Anti-fibrinolytic in Significant Haemorrhage 2) study involved the randomisation of over 20,000 patients with, or at risk of significant haemorrhage in 40 countries. The study demonstrated a 32% reduction in death due to haemorrhage, when tranexamic acid is administered within 1 h of injury. The study concluded that tranexamic acid safely reduced the risk of death in bleeding trauma patients, and should be considered for use in practice.

Following the publication of the study, the Trust has been working with Professor Stuart Logan, Director of the Peninsula National Institute of Health Research's Collaboration for Leadership in Applied Health Research and Care to implement the intervention across the South West.

For further information please contact Adrian South, Deputy Director of Clinical Care at adrian.south@swast.nhs.uk

Local Resources

Published Evidence

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DORSET PARAMEDIC IS THE FIRST BRITISH CITIZEN TO RECEIVE HUMANITARIAN AWARD FROM SERBIAN PRESIDENT
A South Western Ambulance Service paramedic and former soldier has travelled to Serbia and become the first British citizen to receive a Humanitarian Award. Wayne Ingram, who lives in Weymouth, Dorset, joined the ambulance service after leaving the British Army. It was while on patrol with the Army in Bosnia in 2003 that Wayne first met four-year-old Stefan Savic. Stefan had been born with a rare facial cleft that, if left untreated, could have serious health complications, including blindness and the restriction of his airway.
24/02/2017

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